A study has revealed that taking a daily multivitamin for two years may slow some markers of biological aging. Conducted with 958 healthy participants, the research primarily involved older adults with an average age of about 70. This development raises questions about the role of multivitamins in promoting healthier aging.

Study Details and Results

Participants who took a daily multivitamin exhibited a slowdown in biological aging for two of five epigenetic clocks. The changes observed equated to roughly four months less biological aging over the two-year period. The multivitamin used in the study was Centrum Silver, and the research was part of a larger trial examining the effects of cocoa extract and multivitamins on health.

Context and Broader Implications

While these findings are intriguing, several large trials have previously failed to demonstrate meaningful mortality reduction from standard multivitamin supplementation in well-nourished populations. Biological age acceleration is associated with an elevated risk of various diseases, making the implications of this study particularly relevant. However, the study’s findings are not generalizable to other populations, as it only included older adults, mostly white, without major chronic illnesses.

Expert Opinions

Experts express caution regarding the general applicability of these findings. Dr. Dorsa Jalaei stated, “The honest answer, supported by the weight of current evidence, is, for most healthy adults eating a reasonably varied diet, no.” Howard Sesso added, “We are not yet in a position to recommend a daily multivitamin for all older adults,” highlighting the need for further research.

Small Changes and Future Research

Professor Fontana remarked on the study’s findings, saying, “The change was very, very small.” This suggests that while there may be some benefits, they are not substantial enough to warrant widespread recommendations. The science behind epigenetic clocks is still developing and not fully understood, indicating that more research is needed to clarify these results.

Funding and Support

The study was funded by Mars and the US National Institutes of Health, with Pfizer providing additional support. This backing underscores the importance of the research but also raises questions about potential biases in the findings.

Uncertainties and Future Directions

Details remain unconfirmed regarding the specific reasons why daily consumption of multivitamins may have impacted health markers. Furthermore, the long-term effects of multivitamins on healthspan and lifespan remain unconfirmed. They may not reduce disease risk or increase survival despite changes in epigenetic clocks. As research continues, experts hope to explore accessible, safe interventions that contribute to healthier, higher-quality aging.

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A recent study has found that taking a daily multivitamin for two years might slow some markers of biological aging. This finding is particularly significant as it suggests a potential avenue for promoting healthier aging among older adults.

The study involved more than 900 healthy participants, with an average age of about 70. Participants were divided into four groups: those receiving a multivitamin and cocoa extract, those taking cocoa extract and a placebo, those on a multivitamin and a placebo, and a control group receiving two placebos.

Results indicated that those who took a daily multivitamin exhibited a slowdown in biological aging for two of five epigenetic clocks, equating to roughly four months less biological aging over the study period.

Despite these findings, several large trials have previously failed to demonstrate meaningful mortality reduction from standard multivitamin supplementation in well-nourished populations. This raises questions about the practical implications of the new study.

The research was published in the journal Nature Medicine and received a grant from Mars Edge, which included the donation of multivitamins for the research. However, experts remain skeptical about the necessity of multivitamins for healthy adults.

Dr. Dorsa Jalaei stated, “The honest answer, supported by the weight of current evidence, is, for most healthy adults eating a reasonably varied diet, no.” Similarly, Professor Pilar Guallar Castillón advised, “My personal advice is to stop taking multivitamins, whether in pill or gummy form.”

Interestingly, 41 percent of people who take a supplement opt for a multivitamin, according to research from the Food Standards Agency. This statistic highlights the popularity of multivitamins among supplement users.

Dr. Howard Sesso, one of the researchers, noted, “This study opens the door to learning more about accessible, safe interventions that contribute to healthier, higher-quality ageing.” However, Professor Luigi Fontana cautioned that “the magnitude of the effect is extremely small, and the effect was not consistent across all the ageing measures tested.”

Details remain unconfirmed regarding the long-term effects of multivitamin supplementation on biological aging. The study’s findings are not consistent across all aging measures tested, leaving room for further investigation into the role of multivitamins in health.

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On March 4, 2026, Michelle Pfeiffer attended the UK premiere of her new series The Madison at Leicester Square in London. At 67 years old, Pfeiffer continues to captivate audiences with her performances and her evolving perspective on aging.

The Madison, created by Taylor Sheridan, is a neo-Western series that follows the Clyburn family as they navigate the challenges of relocating from New York to the wilderness of Montana. In this series, Pfeiffer plays the role of Stacy Clyburn, with Kurt Russell portraying her husband.

Just prior to the premiere, Pfeiffer was seen at the Saint Laurent Fall/Winter 2026 show in Paris, where she wore a silk black tailored suit. She expressed her appreciation for the event, stating, “Absolutely stunning show! Thank you for having me, @ysl @anthonyvaccarello.” This appearance further highlights her ongoing presence in the fashion world.

As she approaches her 68th birthday on April 29, 2026, Pfeiffer has shared insights into her beauty philosophy, which emphasizes the importance of eating right, exercising, and getting enough sleep. She noted, “I certainly see that I’ve changed. I just try not to dwell on it. Aging happens to every single one of us. Once you accept that, it unburdens you.”

Pfeiffer also reflected on her journey with aging, stating, “The older I’ve gotten, the easier it’s become. You reach a threshold where you’re fine with looking good for your age instead of looking young for your age, and I’ve crossed it.” This perspective resonates with many as societal pressures regarding youthfulness continue to persist.

In addition to her acting career, Pfeiffer celebrated her 32nd anniversary with husband David E. Kelley in November 2025, showcasing her commitment to both her personal and professional life.

Beau Garrett, who is married to Shane Richards, whom she wed in 2025, also attended the premiere, indicating the strong connections within the Hollywood community.

Pfeiffer’s stance on aging includes a critique of excessive cosmetic procedures, as she stated, “What I object to is too much. And really bad plastic surgery. When I think it becomes a distraction and when people don’t look like themselves anymore.” Her candid remarks contribute to the ongoing conversation about beauty standards in the entertainment industry.

As the premiere of The Madison unfolds, Michelle Pfeiffer remains a significant figure in Hollywood, embodying both talent and a refreshing outlook on aging.

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